Lupron Depot® for Prostate Cancer: Efficacy Info from TAP

Proven Testosterone Suppression

Following an initial stimulation, administration of Lupron Depot resulted in suppression of testicular testosterone production, reducing mean testosterone levels to castrate levels within 2-4 weeks. This effect is reversible upon discontinuation of drug therapy.

Mean Serum Testosterone Levels with Lupron Depot 7.5 mg

Mean Serum Testosterone Levels with Lupron Depot® (leuprolide acetate) 7.5mg

Mean Serum Testosterone Levels with Lupron Depot –3 Month 22.5 mg

Mean Serum Testosterone Levels with Lupron Depot® (leuprolide acetate) –3 Month 22.5mg

Mean Serum Testosterone Levels with Lupron Depot –4 Month 30 mg

Mean Serum Testosterone Levels with Lupron Depot® (leuprolide acetate) –4 Month 30mg

Important Safety and Other Information

The most common side effect associated with Lupron Depot is hot flashes. Like other treatment options, LH-RH agonists may cause impotence. Symptoms may worsen over the first few weeks of treatment. Periodic monitoring of PSA and serum testosterone levels is recommended. Lupron Depot -4 Month 30 mg, -3 Month 22.5 mg, and 7.5 mg dosage forms are not indicated for use in women. Lupron Depot is indicated for the palliative treatment of advanced prostate cancer. Individual results may vary. Please see the full Prescribing Information for Lupron Depot -4 Month 30 mg, -3 Month 22.5 mg and 7.5 mg dosage forms and the Patient Product Information.

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Advanced Prostate Cancer Main Hormone Therapy About Lupron Depot Efficacy Dosing & Administration Safety Information Resources for Your Patients Links Using LuproLoc™ Physician Materials Procurement Links	Efficacy of Lupron Depot in Advanced Prostate Cancer As an LH-RH agonist, Lupron Depot acts as a potent inhibitor of gonadotropin secretion. Proven Testosterone Suppression Following an initial stimulation, administration of Lupron Depot resulted in suppression of testicular testosterone production, reducing mean testosterone levels to castrate levels within 2-4 weeks. This effect is reversible upon discontinuation of drug therapy. Mean Serum Testosterone Levels with Lupron Depot 7.5 mg Mean Serum Testosterone Levels with Lupron Depot –3 Month 22.5 mg Mean Serum Testosterone Levels with Lupron Depot –4 Month 30 mg Learn about dosing Lupron Depot	Now you can order Lupron Depot online. Once you've set up an account, it only takes a few clicks. Watch a training video on Lupron Depot administration.

Efficacy of Lupron Depot in Advanced Prostate Cancer

Proven Testosterone Suppression

Mean Serum Testosterone Levels with Lupron Depot 7.5 mg

Mean Serum Testosterone Levels with Lupron Depot –3 Month 22.5 mg

Mean Serum Testosterone Levels with Lupron Depot –4 Month 30 mg

Important Safety and Other Information